Author

J. Valerio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Animal Behavior & Cognition· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

C. Kim· 3 shared M. Kloos· 3 shared M. Sikorski· 3 shared A. Round· 2 shared A. Wrona· 2 shared D. Melo· 2 shared E. Round· 2 shared H. Han· 2 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiochemistry

C. Kim

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Crystal structure of a bacterial photoactivated adenylate cyclase determined at room temperature by serial femtosecond crystallography

S. M. Kapetanaki, N. Coquelle, D. von Stetten, M. Byrdin, R. Rios-Santacruz, R. Bean, J. Bielecki, M. Boudjelida, Z. Fekete, G. W. Grime, H. Han, C. Hatton, S. Kantamneni, K. Kharitonov, C. Kim, , M. Weik

The paper determines the crystal structure of a bacterial photoactivated adenylate cyclase at room temperature using serial femtosecond crystallography and compares it with cryo structures to study structural changes upon light exposure.

bioRxiv · Apr 21, 2024 · PreprintBiophysics

Mix-and-extrude: high-viscosity sample injection towards time-resolved protein crystallography

M. Vakili, H. Han, C. Schmidt, A. Wrona, M. Kloos, I. de Diego, K. Dorner, T. Geng, C. Kim, F. Koua, D. Melo, M. Rappas, A. Round, E. Round, M. Sikorski, , J. Schulz

This paper introduces a mix-and-extrude method for time-resolved protein crystallography using 3D printed microchannels to study ligand-induced reactions in viscous media.

bioRxiv · Nov 23, 2022Biochemistry

Effect of Nrf2 Loss on Senescence and Cognition of Tau-Based P301S Mice

R. T. Riordan, R. Wang, Z. Yu, G. Ross, J. Valerio, J. Dimas-Munoz, V. Heredia, K. R. Magnusson, V. Galvan, V. I. Perez

This study investigates how Nrf2 loss affects senescence and cognition in P301S tauopathy mice, finding that Nrf2 protects brain function through mechanisms beyond senescence inhibition.

bioRxiv · Oct 31, 2022Animal Behavior & Cognition

Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX

L. J. Williamson, M. Galchenkova, H. L. Best, R. J. Bean, A. Munke, S. Awel, G. Pena, J. Knoska, R. Schubert, K. Doerner, H.-W. Park, D. K. Bideshi, A. Henkel, V. Kremling, B. Klopprogge, , D. Oberthur

This paper determines the structure of Tpp49Aa1 using MHz-SFX and investigates its interaction with Cry48Aa1, expanding its known target range to include additional mosquito species.

bioRxiv · Jan 14, 2022 · PreprintBiochemistry