Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion
R. F. Frausto, V. S. Swamy, G. S. Peh, P. M. Boere, E. M. Hanser, D. D. Chung, B. L. George, M. Morselli, L. Kao, R. Azimov, J. Wu, M. Pellegrini, I. Kurtz, J. S. Mehta, A. J. Aldave
This study compares two methods for expanding human corneal endothelial cells in vitro, finding that low mitogenic conditions better preserve cell identity and that senescence occurs with continuous passaging.
bioRxiv · Sep 4, 2019Cell Biology