Microenvironmental Stiffness Induces Metabolic Reprogramming in Glioblastoma
A. Sohrabi, A. E. Y. T. Lefebvre, M. J. Harrison, M. C. Condro, T. M. Sanazzaro, G. Safarians, I. Solomon, S. Bastola, S. Kordbacheh, N. Toh, H. I. Kornblum, M. A. Digman, S. K. Seidlits
This study shows that a softer matrix microenvironment induces glioblastoma cells to shift toward glycolysis, increasing migration and decreasing proliferation.
bioRxiv · Jul 3, 2023Cancer Biology