Author

S. K. Seidlits

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sohrabi· 2 shared S. Bastola· 2 shared A. Burlingame· 1 shared A. E. Y. T. Lefebvre· 1 shared A. Hjelmeland· 1 shared D. Muthukrishnan· 1 shared D. Yamashita· 1 shared G. Safarians· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. Sohrabi

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2 papers

Recent·Most cited

Microenvironmental Stiffness Induces Metabolic Reprogramming in Glioblastoma

A. Sohrabi, A. E. Y. T. Lefebvre, M. J. Harrison, M. C. Condro, T. M. Sanazzaro, G. Safarians, I. Solomon, S. Bastola, S. Kordbacheh, N. Toh, H. I. Kornblum, M. A. Digman, S. K. Seidlits

This study shows that a softer matrix microenvironment induces glioblastoma cells to shift toward glycolysis, increasing migration and decreasing proliferation.

bioRxiv · Jul 3, 2023Cancer Biology

Endothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma

S. Bastola, M. S. Pavlyukov, Y. Ghochani, N. Sharma, M. A. Nakano, D. Muthukrishnan, S. Y. Yu, M. S. Kim, A. Sohrabi, N. P. Biscola, D. Yamashita, K. Anufrieva, R. Kawaguchi, Y. Qin, S. K. Seidlits, , H. Kornblum

This study identifies Endocan as an endothelial-secreted ligand for PDGFR alpha that promotes GBM vascularity, radioresistance, and phenotypic diversity.

bioRxiv · Oct 12, 2020 · PreprintCancer Biology