Long-chain fatty acyl-coenzyme A activates the mitochondrial fission factors MiD49 and MiD51 by inducing their oligomerization
A. Liu, F. Kage, G. Sapp, H. Aydin, H. N. Higgs
This study shows that long-chain fatty acyl-CoA activates mitochondrial fission proteins MiD49 and MiD51 by inducing their oligomerization, which enhances DRP1 GTPase activity and promotes mitochondrial fission.
bioRxiv · Jul 31, 2023 · PreprintCell Biology