Protective low avidity anti-tumour CD8+ T cells are selectively attenuated by regulatory T cells
G. Sugiyarto, D. Prossor, O. Dadas, T. Elliott, E. James
The paper shows that regulatory T cells suppress protective anti-tumour CD8+ T cell responses by inducing low avidity T cells that are more effective in tumour rejection.
bioRxiv · Nov 29, 2018Immunology