BiochemistryCellPeer-reviewed
DNA end sensing and cleavage by the Shedu anti-phage defense system
L. Loeff, A. Walter, G. T. Rosalen, M. Jinek
This study characterizes the Shedu anti-phage defense system, revealing its DNA end recognition and cleavage mechanism, and shows how phages evade it by altering DNA replication.
DOI 10.1016/j.cell.2024.11.030