Author

G. V. Klink

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 4

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Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. A. Bazykin· 4 shared A. A. Penin· 1 shared A. V. Cherkasov· 1 shared A. V. Golovin· 1 shared D. Biba· 1 shared D. Pemba· 1 shared E. I. Shagimardanova· 1 shared G. R. Gazizova· 1 shared

Activity by Year

2017-2021 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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4 shared papersEvolutionary Biology

G. A. Bazykin

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4 papers

Recent·Most cited

Phylogenetic inference of changes in amino acid propensities with single-position resolution

G. V. Klink, O. V. Kalinina, G. A. Bazykin

This paper develops a method to detect changes in amino acid fitness across lineages using phylogenetic and sequence data, validated on HIV-1 and influenza A proteins.

bioRxiv · Jan 7, 2021Evolutionary Biology

Pairs of compensatory frameshifting mutations contribute to evolution of protein-coding sequences in vertebrates and insects

D. Biba, G. V. Klink, G. A. Bazykin

The paper identifies pairs of compensatory frameshifting mutations in vertebrates and insects, showing they generate novel protein sequences and contribute to evolutionary diversity.

bioRxiv · Dec 25, 2020 · PreprintEvolutionary Biology

Population genomics of two closely related anhydrobiotic midges reveals differences in adaptation to extreme desiccation

N. M. Shaykhutdinov, G. V. Klink, S. K. Garushyants, O. S. Kozlova, A. V. Cherkasov, T. Kikawada, T. Okuda, D. Pemba, R. M. Deviatiiarov, G. R. Gazizova, A. A. Penin, E. I. Shagimardanova, R. Cornette, O. A. Gusev, G. A. Bazykin

This study compares the population genomics of two anhydrobiotic midges, revealing differences in the genetic architecture and adaptation of the PIMT gene family to desiccation.

bioRxiv · Aug 19, 2020Evolutionary Biology

Pathogenic Amino Acid Variants In Mitochondrial Proteins More Frequently Arise In Lineages Closely Related To Human Than In Distant Lineages

G. V. Klink, A. V. Golovin, G. A. Bazykin

The paper shows that pathogenic amino acid variants in human mitochondrial proteins are more common in closely related species than distant ones, suggesting these variants are more tolerated in humans.

bioRxiv · Jul 21, 2017Evolutionary Biology