Author

T. Kikawada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:Drosophila· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

O. Gusev· 3 shared R. Cornette· 3 shared S. Kikuta· 2 shared S. Tokumoto· 2 shared Y. Miyata· 2 shared A. A. Penin· 1 shared A. Nesmelov· 1 shared A. V. Cherkasov· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

O. Gusev

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Sodium-dependent Trehalose Transporter Contributes to Anhydrobiosis in Insect Cell Line, Pv11

K. Mizutani, Y. Yoshida, E. Nakanishi, Y. Miyata, S. Tokumoto, H. Fuse, O. Gusev, S. Kikuta, T. Kikawada

This paper identifies STRT1, a sodium-dependent trehalose transporter in Pv11 cells, which is essential for recovery from anhydrobiosis by regulating intracellular osmolality during rehydration.

bioRxiv · Sep 29, 2023Biochemistry

Population genomics of two closely related anhydrobiotic midges reveals differences in adaptation to extreme desiccation

N. M. Shaykhutdinov, G. V. Klink, S. K. Garushyants, O. S. Kozlova, A. V. Cherkasov, T. Kikawada, T. Okuda, D. Pemba, R. M. Deviatiiarov, G. R. Gazizova, A. A. Penin, E. I. Shagimardanova, R. Cornette, O. A. Gusev, G. A. Bazykin

This study compares the population genomics of two anhydrobiotic midges, revealing differences in the genetic architecture and adaptation of the PIMT gene family to desiccation.

bioRxiv · Aug 19, 2020Evolutionary Biology

Development of a Tet-On inducible expression system for the anhydrobiotic cell line, Pv11

S. Tokumoto, Y. Miyata, K. Usui, R. Deviatiiarov, T. Ohkawa, S. Kondratieva, E. Shagimardanova, O. Gusev, R. Cornette, M. Itoh, Y. Hayashizaki, T. Kikawada

The paper develops a Tet-On inducible expression system for the desiccation-tolerant Pv11 cell line, demonstrating successful expression of reporter genes and a complex enzyme.

bioRxiv · May 29, 2020Bioengineering

Towards Water-Free Biobanks: Long-Term Dry-Preservation At Room Temperature Of Desiccation-Sensitive Enzyme Luciferase In Air-Dried Insect Cells

S. Kikuta, S. J. Watanabe, R. Sato, O. Gusev, A. Nesmelov, Y. Sogame, R. Cornette, T. Kikawada

This study demonstrates that desiccation-tolerant insect cells can preserve exogenous luciferase activity for over 372 days at room temperature through a trehalose preincubation process.

bioRxiv · Mar 24, 2017Biochemistry