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G. Y. P. Poon

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Evolutionary Biology· 1

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

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C. J. Watson· 1 shared D. S. Fisher· 1 shared J. R. Blundell· 1 shared

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1 shared paperEvolutionary Biology

C. J. Watson

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Evolutionary BiologybioRxivOct 8, 2020

Synonymous mutations reveal genome-wide driver mutation rates in healthy tissues

G. Y. P. Poon, C. J. Watson, D. S. Fisher, J. R. Blundell

The paper estimates genome-wide driver mutation rates in healthy tissues using synonymous passenger mutations and finds many driver mutations occur outside of known cancer genes in blood but not in oesophagus.

DOI 10.1038/s41588-021-00957-1

humanwhole-genome sequencing

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