D. S. Fisher

Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population

The paper shows that hybridization drives genomic diversity in a cyanobacterial population despite ecological barriers, challenging the idea that such barriers prevent long-term genomic mixing.

Spatiotemporal Ecological Chaos Enables Gradual Evolutionary Diversification Without Niches or Tradeoffs

This paper shows that spatiotemporal ecological chaos allows indefinite diversification of bacterial strains without niches or tradeoffs.

Inevitability of Red Queen evolution driven by organismic complexity and simple feedback via environmental modification

The paper shows that Red Queen dynamics emerge from organismic complexity and environmental feedback, with evolution perpetually wandering without converging to fitness maxima.

Population genetics of polymorphism and divergence in rapidly evolving populations

This paper extends the traveling wave framework to intermediate regimes of mutation fitness effects, deriving new expressions for fixation probabilities and site frequency spectra.

Synonymous mutations reveal genome-wide driver mutation rates in healthy tissues

The paper estimates genome-wide driver mutation rates in healthy tissues using synonymous passenger mutations and finds many driver mutations occur outside of known cancer genes in blood but not in oesophagus.

Adaptive walks on high-dimensional fitness landscapes and seascapes with distance-dependent statistics

This paper introduces high-dimensional fitness landscapes with distance-dependent statistics to study adaptive walks and evolutionary dynamics, showing that past evolution significantly conditions future adaptive potential.

Stabilization of extensive fine-scale diversity by spatio-temporal chaos

The paper shows that spatio-temporal chaos can stabilize extensive microbial diversity without niche differences, using generalized Lotka-Volterra models with anti-symmetric interactions.

Modeling the interplay between plastic tradeoffs and evolution in changing environments

The paper presents a model showing how evolutionary history influences tradeoff strength and future evolution in changing environments.

Rapid adaptation in large populations with very rare sex: scalings and spontaneous oscillations

This paper studies adaptation in large populations with rare sex, finding that adaptation speed depends on log(Nr)/log(N) and reveals spontaneous oscillations between mutation and reassortment phases.

The dynamics of adaptive genetic diversity during the early stages of clonal evolution

This study investigates genetic diversity dynamics in clonally evolving populations, finding predictable early increases followed by a diversity crash due to highly-fit double mutants.