Author

C. J. Watson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. J. MacNeil· 2 shared K. C. Whitley· 2 shared R. E. MacPherson· 2 shared A. A. Marais· 1 shared A. T. Monstad-Rios· 1 shared B. D. Roy· 1 shared B. Hockey· 1 shared B. J. Baranowski· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersPhysiology

A. J. MacNeil

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

GSK3 inhibition improves skeletal muscle function and whole-body metabolism in the severe DBA/2J mdx mouse model

B. M. Marcella, B. Hockey, J. L. Braun, K. C. Whitley, M. S. Geromella, R. W. Baranowski, C. J. Watson, S. Silvera, S. I. Hamstra, L. J. Wasilewicz, R. W. Crozier, A. A. Marais, R. Vandenboom, B. D. Roy, A. J. MacNeil, , V. Fajardo

This study shows that GSK3 inhibition improves skeletal muscle function and insulin sensitivity in mdx mice, either alone or combined with exercise.

bioRxiv · Feb 16, 2022 · PreprintPhysiology

Kynurenine metabolism is altered in mdx mice: a potential muscle to brain connection

E. N. Copeland, K. C. Whitley, C. J. Watson, B. J. Baranowski, N. Kurgan, A. J. MacNeil, R. E. MacPherson, V. A. Fajardo, D. J. Allison

This study shows that KYN metabolism is altered in D2 mdx mice, with reduced KYNA and KYNA:KYN ratio and anxiety-like behaviors, suggesting a link between muscle disease and brain metabolism.

bioRxiv · Jan 14, 2022Physiology

Synonymous mutations reveal genome-wide driver mutation rates in healthy tissues

G. Y. P. Poon, C. J. Watson, D. S. Fisher, J. R. Blundell

The paper estimates genome-wide driver mutation rates in healthy tissues using synonymous passenger mutations and finds many driver mutations occur outside of known cancer genes in blood but not in oesophagus.

bioRxiv · Oct 8, 2020Evolutionary Biology

ScreenCube: A 3D Printed System For Rapid and Cost-Effective Chemical Screening in Adult Zebrafish

A. T. Monstad-Rios, C. J. Watson, R. Y. Kwon

This study introduces a 3D printed system for rapid, cost-effective chemical screening in adult zebrafish, demonstrating its ability to identify known inhibitors of tail fin regeneration.

bioRxiv · Jul 14, 2017Pharmacology & Toxicology