Macrophage efferocytosis is controlled by epigenetic modifications mediated by RBPJ
Samreen Sadaf, Xinyi Zhang, Liqun Lei, Jixing Shen, Imran Jamal, Ganesh Modugu, Partha Dutta
This study identifies RBPJ-mediated epigenetic regulation of efferocytosis in macrophages, showing that suppression of H3K9me3 enhances apoptotic cell clearance and suppresses inflammation.
bioRxiv · Oct 10, 2025 · PreprintImmunology