Author

Xinyi Zhang

University of PittsburghORCID 0000-0002-5846-337XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xinyi Zhang10 papers · Central China Normal University

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Azeez ButaliiD· 1 shared Carmen J. BuxóiD· 1 shared Carmencita David PadillaiD· 1 shared Dan YiiD· 1 shared Eleanor FeingoldiD· 1 shared Elizabeth J. LeslieiD· 1 shared Ganesh Modugu· 1 shared George L. WehbyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Azeez ButaliORCID

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Author profile →

3 papers

Recent·Most cited

CD133+ progenitor cells promote pulmonary hypertension through CXCR4 signaling

Zhiqing Wang, Dan Yi, Xinyi Zhang, Jingbo Dai, Xianming Zhang, You‐Yang Zhao, Zhiyu Dai

This study identifies CD133+ progenitor cells as contributors to pulmonary hypertension and shows that CXCR4 signaling drives their pathogenic role in vascular remodeling.

bioRxiv · Aug 2, 2026 · PreprintPathology

Macrophage efferocytosis is controlled by epigenetic modifications mediated by RBPJ

Samreen Sadaf, Xinyi Zhang, Liqun Lei, Jixing Shen, Imran Jamal, Ganesh Modugu, Partha Dutta

This study identifies RBPJ-mediated epigenetic regulation of efferocytosis in macrophages, showing that suppression of H3K9me3 enhances apoptotic cell clearance and suppresses inflammation.

bioRxiv · Oct 10, 2025 · PreprintImmunology

Variants in CALD1, ESRP1, and RBFOX1 are associated with orofacial cleft risk

Jenna C. Carlson, Xinyi Zhang, Zeynep Erdogan-Yildirim, Terri H. Beaty, Azeez Butali, Carmen J. Buxó, Lord Jephthah Joojo Gowans, Jacqueline T. Hecht, Ross E. Long, Lina Johanna Moreno, Jeffrey Clark Murray, Ieda Maria Orioli, Carmencita David Padilla, George L. Wehby, Eleanor Feingold, , John R. Shaffer

This study identifies three new genetic loci associated with orofacial cleft risk and confirms known risk genes, providing insights into the molecular mechanisms of facial development.

medRxiv · Jan 21, 2025 · PreprintGenetic & Genomic Medicine