Human tissue-resident CD8 T cells contribute to trophoblast homeostasis in health and during acute inflammation
Caitlin S. DeJong, Marie Frutoso, Nicole B. Potchen, Geervani Daggupati, A Konecny, Yin Huang, Manu N. Setty, Swati Shree, Stephen A. McCartney, Martin Prlic
The paper examines how T cell-tissue cell communication changes in human placental tissue during acute inflammation, finding that tissue-resident CD8 T cells support trophoblast homeostasis in both healthy and inflamed states.
bioRxiv · Jun 9, 2026 · PreprintImmunology