Dysregulation of epithelial differentiation architecture underlies field cancerization in head and neck cancer
Claire Mills, Yin Huang, Chan Mi Lee, Connor Finkbeiner, Rachel K. Lex, Dominik J. Otto, Ruijin Yang, Hoku West‐Foyle, Daniel Jones, Annalyssa Long, Sam Minot, Emma Nguyen, Pushpa Itagi, Samantha Schuster, Anna Elz, , Slobodan Beronja
This study identifies molecular and architectural changes in normal-adjacent field tissue in HNSCC that disrupt epithelial differentiation and may promote cancer development.
bioRxiv · Oct 14, 2026 · PreprintCancer Biology