Coordinated expansion of CD163⁺ monocytes and immature CD177⁺ neutrophils marks severe neurotoxicity after CD19 CAR T cell therapy
Tony Chour, Nikhita H. Poole, Hugh R. MacMillan, Katelyn Burleigh, David Richard Glass, Emily C. Liang, Ryan Basom, Bobbie‐Jo Webb‐Robertson, Kelly Stratton, Derrik Gratz, Annalyssa N. Long, Anna Elz, Jennifer Jing Huang, Alexandre V. Vinaud Hirayama, Stanley R. Riddell, , Sylvain Simon
The paper identifies CD163+ monocytes and immature CD177+ neutrophils as markers of severe neurotoxicity after CD19 CAR T cell therapy through multi-omics profiling.
bioRxiv · Jul 9, 2026 · PreprintImmunology