A scalable genetic tool for the functional analysis of the signal recognition particle.
Lawton F. Long, Shivani Biskunda, Ming Yang, George C. Wu, Cassidy F Simas, Steven D. Bruner, Carl A. Denard
This paper develops a yeast haploid model to study SRP54 mutations and their functional consequences, revealing dominant-negative phenotypes and growth defects associated with specific mutations.
bioRxiv · Jul 20, 2024 · PreprintSynthetic Biology