A conserved differentiation program facilitates inhibitory neuron production in the developing mouse and human cerebellum
Jens Bager Christensen, Alex P. A. Donovan, Marzieh Moradi, Giada Vanacore, Mohab Helmy, Adam James Reid, Jimmy Tsz Hang Lee, Omer Ali Bayraktar, Andrea H. Brand, Nermin Sumru Bayin
The paper identifies FOXO1 as a key regulator of inhibitory neuron differentiation in mouse and human cerebellar progenitors, showing its conservation and regulation by WNT signaling.
bioRxiv · Apr 10, 2025 · PreprintDevelopmental Biology