Human IRAK kinases differentially alter metabolic regulation and mitochondrial function in Saccharomyces cerevisiae
Elba del Val, Giulia Genna, Teresa Fernández‐Acero, Marı́a Molina, Vı́ctor J. Cid
This study expresses human IRAK1, IRAK2, and IRAK4 in yeast to analyze their effects on metabolism and mitochondrial function, identifying IRAK4's role in growth inhibition and metabolic deregulation.
bioRxiv · Aug 6, 2025 · PreprintCell Biology