Vı́ctor J. Cid

In vivo functional classification of PTEN variants reveals context-dependent oncogenicity and interindividual variability

The paper assesses PTEN variant functionality across species, showing context-dependent oncogenicity and interindividual variability using C. elegans and cell lines.

Human IRAK kinases differentially alter metabolic regulation and mitochondrial function in Saccharomyces cerevisiae

This study expresses human IRAK1, IRAK2, and IRAK4 in yeast to analyze their effects on metabolism and mitochondrial function, identifying IRAK4's role in growth inhibition and metabolic deregulation.

Heterologous expression of human pro-inflammatory Caspase-1 in Saccharomyces cerevisiae and comparison to pro-apoptotic Caspase-8

This study expresses human Caspase-1 and Caspase-8 in yeast, comparing their effects on cell death and organelle damage, finding Caspase-8 more aggressive and identifying Bni1 as a substrate.