Integral Gene Drives: an \"operating system\" for population replacement
Alexander Nash, Giulia Mignini Urdaneta, Andrea K. Beaghton, Astrid Hoermann, Philippos Aris Papathanos, George K. Christophides, Nikolai Windbichler
This paper evaluates Integral Gene Drive (IGD) as a more durable and flexible alternative to classical gene drives for population replacement, showing reduced resistance and prolonged transmission blockage.
bioRxiv · Jun 28, 2018 · PreprintSynthetic Biology