Author

Andrea K. Beaghton

Imperial College LondonORCID 0000-0002-2403-186XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:CRISPR screen· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander NashiD· 1 shared Andrea CrisantiiD· 1 shared Andrew HammondiD· 1 shared Astrid HoermanniD· 1 shared Austin BurtiD· 1 shared George K. ChristophidesiD· 1 shared Giulia Mignini Urdaneta· 1 shared Ioanna MorianouiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Alexander NashORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 4, 2020

Regulation of gene drive expression increases invasive potential and mitigates resistance

Andrew Hammond, Xenia Karlsson, Ioanna Morianou…·Tony Nolan

This study improves gene drive efficacy by reducing resistance and fitness costs through regulatory sequence modifications, leading to better population suppression and delayed resistance.

29 citations

statistical modelexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintJun 28, 2018

Integral Gene Drives: an \"operating system\" for population replacement

Alexander Nash, Giulia Mignini Urdaneta, Andrea K. Beaghton…·Nikolai Windbichler

This paper evaluates Integral Gene Drive (IGD) as a more durable and flexible alternative to classical gene drives for population replacement, showing reduced resistance and prolonged transmission blockage.

1 citation

CRISPR screenstatistical model

𝕏 PostBluesky