Simultaneously inferring T cell fate and clonality from single cell transcriptomes
Michael J.T. Stubbington, Tapio Lönnberg, Valentina Proserpio, Simon Clare, Anneliese O. Speak, Gordon Dougan, Sarah A. Teichmann
This paper introduces TraCeR, a method to infer full-length TCR sequences from single-cell RNA-seq, revealing clonal relationships and linking them to T cell functional states in Salmonella infection.
Nature Methods · Mar 7, 2016Peer-reviewedBioinformatics