Valine restriction extends survival in a Drosophila model of short-chain enoyl-CoA hydratase 1 (ECHS1) deficiency
Sarah Mele, Felipe Martelli, Christopher K. Barlow, Grace Jefferies, Sebastian Dworkin, John Christodoulou, Ralf B. Schittenhelm, Matthew D. W. Piper, Travis K. Johnson
This study establishes a Drosophila model of ECHS1 deficiency and shows that valine restriction improves larval survival.
bioRxiv · Aug 15, 2024 · PreprintGenetics