The INO80 Chromatin Remodeler Sustains Metabolic Stability by Promoting TOR Signaling and Regulating Histone Acetylation
Sean L. Beckwith, Erin K. Schwartz, Pablo E. García-Nieto, Devin A. King, Graeme J. Gowans, Ka Man Wong, Wei Yao, Tessa L. Eckley, Alexander P. Paraschuk, Egan L. Peltan, Laura R. Lee, Ashby J. Morrison
This study identifies the INO80 chromatin remodeler's role in metabolic stability through TOR signaling and histone acetylation regulation in yeast, with implications for human cancer.
PLoS Genetics · Feb 20, 2018Peer-reviewedGenetics