Alicia N. Schep

The paper introduces Pi-ATAC, a method combining single-cell chromatin and proteomic profiling, revealing hypoxia's role in shaping the regulome in tumor cells.

This paper introduces scABC, an R package for unsupervised clustering of scATAC-seq data to classify cell types based on open chromatin regions.

This study shows that the INO80 chromatin-remodelling complex coordinates metabolic homeostasis with cell division in S. cerevisiae by regulating periodic gene expression.

chromVAR analyzes sparse scATAC-seq data to estimate motif-associated accessibility changes and cluster profiles while controlling technical biases.

The paper uses single-cell chromatin accessibility to map the continuous regulatory variation in human hematopoietic differentiation and identifies epigenomic heterogeneity within cell populations.