Author

Grant de Jong

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

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Assay:ATAC-seq· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Fani MemiiD· 2 shared Manu SaraswatiD· 2 shared Moritz MalliD· 2 shared Oliver Gould· 2 shared Oliver StegleiD· 2 shared Omer Ali BayraktariD· 2 shared Richard James MairiD· 2 shared Tannia GraciaiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Fani MemiORCID

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2 papers

Recent·Most cited

A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity

Grant de Jong, Fani Memi, Tannia Gracia, Olga Lazareva, Oliver Gould, Alexander Aivazidis, Manàs Dave, Qianqian Zhang, Melanie P. Jensen, Ahmet Süreyya Rifaioğlu, João Diogo Barros-Silva, Sabine E. Eckert, Di Zhou, Yvette Wood, Elizabeth J. Tuck, , Omer Ali Bayraktar

The paper identifies a spatiotemporal cancer cell trajectory in glioblastoma that explains tumor heterogeneity across regions and subclones.

bioRxiv · May 13, 2025 · PreprintCancer Biology

Decoding Plasticity Regulators and Transition Trajectories in Glioblastoma with Single-cell Multiomics

Manu Saraswat, Laura Rueda-Gensini, Elisa Heinzelmann, Tannia Gracia, Fani Memi, Grant de Jong, Jannes Straub, Cedar Schloo, Dirk C. Hoffmann, Erik Jung, Tim Kindinger, Bettina Weigel, Bryce Lim, Sophie Weil, Oliver Gould, , Moritz Mall

This study uses single-cell multiomics to identify regulatory programs and plasticity regulators in glioblastoma, revealing MYT1L as a key repressor of malignant plasticity.

bioRxiv · May 13, 2025 · PreprintCancer Biology