Author

Guijie Zhu

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Organism:E. coli· 1

Frequent Co-Authors

Liangliang SuniD· 3 shared Guangyao Gao· 2 shared Seyed Amirhossein Sadeghi· 2 shared Yifan Yue· 2 shared Ali Akbar AshkarraniD· 1 shared Fei FangiD· 1 shared Jorge A. Colón-RosadoiD· 1 shared Morteza MahmoudiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersSystems Biology

Liangliang SunORCID

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3 papers

Recent·Most cited

Proteoform Barcode: An Intuitive Visualization Framework for Top-Down Proteomics

Yifan Yue, Guangyao Gao, Fei Fang, Guijie Zhu, Seyed Amirhossein Sadeghi, Reyhane Tabatabaeian Nimavard, Liangliang Sun

The paper introduces a visualization framework for top-down proteomics data, called proteoform barcode, which displays proteoform abundance and functional information, enabling disease diagnosis.

bioRxiv · Aug 18, 2026 · PreprintSystems Biology

Decades of dreams coming true: capillary zone electrophoresis-mass spectrometry for reproducible multi-level proteomics

Guijie Zhu, Yifan Yue, Jorge A. Colón-Rosado, Guangyao Gao, Xiaowen Liu, Liangliang Sun

The paper demonstrates that capillary zone electrophoresis-mass spectrometry (CZE-MS) can reproducibly measure peptides, proteoforms, and complexoforms across multiple biological samples.

bioRxiv · Jan 31, 2026 · PreprintSystems Biology

Mass spectrometry-based top-down proteomics in nanomedicine: proteoform-specific measurement of protein corona

Seyed Amirhossein Sadeghi, Ali Akbar Ashkarran, Qianyi Wang, Guijie Zhu, Morteza Mahmoudi, Liangliang Sun

This study introduces a top-down proteomics method to precisely identify proteoforms in nanoparticle protein coronas, revealing biomarkers not detectable by bottom-up approaches.

ACS Nano · Sep 14, 2024Peer-reviewedSystems Biology