Qianyi Wang

This study identifies mitochondrial scaffolds that regulate PIWI protein trafficking and pachytene piRNA biogenesis in mice, revealing a central role for chromatoid body precursors in piRNA complex formation.

This paper demonstrates that adding small molecules to plasma enhances nanoparticle protein corona diversity, significantly increasing the number of detectable proteins in plasma proteome profiling.

This study shows that PNLDC1 is essential for piRNA 3' end trimming, LINE1 silencing, and spermatogenesis in mice, with pachytene piRNA trimming being critical for germ cell development.

This study introduces a top-down proteomics method to precisely identify proteoforms in nanoparticle protein coronas, revealing biomarkers not detectable by bottom-up approaches.

This paper introduces a new native proteomics technique using nCZE-MS to measure proteoforms and protein complexes in complex samples, achieving high sensitivity and resolution.