Gulay Dagdas

Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface

This paper compares single-cell data across six mammalian species to uncover evolutionary patterns in cell types and signaling at the fetal-maternal interface, finding conserved gene signatures and stepwise evolution of decidual cells.

Hallmarks of uterine receptivity predate placental mammals

This paper compares single-cell transcriptomes of uterine and embryonic tissues across rodents and opossums to show that marsupial uteri activate an ancestral signaling axis similar to eutherian implantation, but with inhibitory signals preventing invasion.

A SNP affects Wnt4 expression in endometrial stroma, with antagonistic implications for pregnancy, endometriosis and reproductive cancers

This study identifies a SNP that affects Wnt4 expression in endometrial stroma, linking it to pregnancy, endometriosis, and reproductive cancers through differential gene regulation.