Author

Chao Fang

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Chunhui HouiD· 1 shared Edwin Chong Wing CheungiD· 1 shared Etai JacobiD· 1 shared Guowei LiiD· 1 shared Gustavo Arango-Argoty· 1 shared Ioannis Kagiampakis· 1 shared Jiacheng WangiD· 1 shared Jialei SuniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenetics

Chunhui HouORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Speciesformer learns conserved cellular states for cross-species generative virtual cell modeling

Jiacheng Wang, Jiaqi Dong, Guowei Li, Chao Fang, Liwei Liu, Xin Gao

Speciesformer learns conserved cellular states across species to enable cross-species generative modeling of virtual cell states and their responses to interventions.

bioRxiv · Sep 23, 2026 · PreprintSystems Biology

Integrating Knowledge Graphs into Machine Learning Models for Survival Prediction and Biomarker Discovery in Patients with Non-Small-Cell Lung Cancer

Chao Fang, Gustavo Arango-Argoty, Ioannis Kagiampakis, Mohammad Hassan Khalid, Etai Jacob, Krishna C. Bulusu, Natasha Markuzon

The paper integrates knowledge graphs into machine learning models to improve survival prediction and biomarker discovery in non-small-cell lung cancer patients, showing significant improvements in hazard ratios and overall survival differentiation.

bioRxiv · Feb 29, 2024 · PreprintBioinformatics

Systematic Chromatin Architecture Analysis in Xenopus tropicalis Reveals Conserved Three-Dimensional Folding Principles of Vertebrate Genomes

Longjian Niu, Wei Shen, Zhaoying Shi, Yongjun Tan, Na He, Jing Wan, Jialei Sun, Yuedong Zhang, Yingzhang Huang, Wenjing Wang, Chao Fang, Jiashuo Li, Piaopiao Zheng, Edwin Chong Wing Cheung, Yonglong Chen, , Chunhui Hou

This study analyzes chromatin architecture in Xenopus tropicalis, revealing TAD formation dynamics and conserved CTCF-Rad21 orientation patterns across vertebrates.

Nature Genetics · Jun 7, 2021Peer-reviewedGenetics