Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose
D. Laurent, F. Semple, P. J. Starkey Lewis, E. Rose, H. A. Black, S. J. Forbes, M. J. Arends, J. W. Dear, T. J. Aitman
This study directly measures the tissue origins of cell-free DNA in healthy mice and after paracetamol overdose, showing increased liver contribution in cases of liver injury.
bioRxiv · Jul 26, 2019Pharmacology & Toxicology