Author

H. Abdizadeh

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Evolutionary Biology· 1

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. R. Atilgan· 1 shared C. Atilgan· 1 shared E. Toprak· 1 shared I. K. Gaszek· 1 shared K. Reynolds· 1 shared T. Batur· 1 shared Y. T. Tamer· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. R. Atilgan

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1 paper

Recent·Most cited

High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection

Y. T. Tamer, I. K. Gaszek, H. Abdizadeh, T. Batur, K. Reynolds, A. R. Atilgan, C. Atilgan, E. Toprak

The paper quantifies high-order epistasis in DHFR mutations under trimethoprim selection, revealing complex fitness landscapes and implications for inhibitor design.

bioRxiv · Aug 22, 2018Evolutionary Biology