Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization
G. kanfer, S. A. Sarraf, Y. Maman, H. Baldwin, K. R. Johnson, M. E. Ward, M. Kampmann, J. Lippincott-Schwartz, R. J. Youle
The paper introduces AI-Photoswitchable Screening (AI-PS) to identify genes affecting subcellular localization, validating factors involved in TFEB relocation.
bioRxiv · Jul 2, 2020Cell Biology