Author

M. E. Ward

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1

Frequent Co-Authors

G. kanfer· 2 shared M. Kampmann· 2 shared M. S. Fernandopulle· 2 shared R. J. Youle· 2 shared S. A. Sarraf· 2 shared A. Pandit· 1 shared A. V. Prabhu· 1 shared C. H. Ludwig· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

G. kanfer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Large structural variants in KOLF2.1J are unlikely to compromise neurological disease modelling

M. Ryan, J. A. McDonough, M. E. Ward, M. R. Cookson, W. C. Skarnes, F. T. Merkle

The paper evaluates CNVs in a hiPSC line and concludes that their potential impact on neurological disease modelling is outweighed by the line's benefits.

bioRxiv · Jan 29, 2024 · PreprintCell Biology

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes

J. Nixon-Abell, F. S. Ruggeri, S. Qamar, T. W. Herling, M. A. Czekalska, Y. Shen, G. Wang, C. King, M. S. Fernandopulle, T. Sneideris, J. L. Watson, V. V. Pillai, W. Meadows, J. Henderson, J. E. Chambers, , P. St George Hyslop

This study shows ANXA11 biomolecular condensates couple protein and lipid phase states on lysosomal membranes through interactions with ALG2 and CALC.

bioRxiv · Mar 22, 2023Cell Biology

Conformational dynamics of photosynthetic Light-Harvesting Complex II in a native membrane environment

F. Azadi-Chegeni, M. E. Ward, G. Perin, D. Simionato, T. Morosinotto, M. Baldus, A. Pandit

This study uses solid-state NMR to analyze conformational dynamics of LHCII in native thylakoid membranes, identifying flexible sites and reduced dynamics in native organelles.

bioRxiv · Aug 20, 2020Biophysics

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

G. kanfer, S. A. Sarraf, Y. Maman, H. Baldwin, K. R. Johnson, M. E. Ward, M. Kampmann, J. Lippincott-Schwartz, R. J. Youle

The paper introduces AI-Photoswitchable Screening (AI-PS) to identify genes affecting subcellular localization, validating factors involved in TFEB relocation.

bioRxiv · Jul 2, 2020Cell Biology

CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons

R. Tian, M. A. Gachechiladze, C. H. Ludwig, M. T. Laurie, J. Y. Hong, D. Nathaniel, A. V. Prabhu, M. S. Fernandopulle, R. Patel, M. Abshari, M. E. Ward, M. Kampmann

This study develops a CRISPRi platform for genetic screens in human iPSC-derived neurons, identifying gene knockdown effects on survival, transcriptomics, and morphology.

bioRxiv · Jul 3, 2019Cell Biology

Selective autophagic clearance of protein aggregates is mediated by the autophagy receptor, TAX1BP1

S. A. Sarraf, H. V. Shah, G. Kanfer, M. E. Ward, R. J. Youle

This study identifies TAX1BP1 as a key autophagy receptor mediating selective clearance of protein aggregates, including polyQ proteins, through autophagy.

bioRxiv · Mar 9, 2019 · PreprintCell Biology