Quantitative and molecular differences distinguish adult human medullary and extramedullary haematopoietic stem and progenitor cell landscapes
N. Mende, H. Bastos, A. Santoro, K. Sham, K. T. Mahbubani, A. Curd, H. Takizawa, N. K. Wilson, B. Gottgens, K. Saeb-Parsy, E. Laurenti
This study compares HSPC landscapes in bone marrow, spleen, and peripheral blood using single-cell RNA-seq, revealing distinct molecular and functional differences in haematopoiesis across these sites.
bioRxiv · Jan 26, 2020 · PreprintCell Biology