Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling on intestinal epithelial cells
d. w. El-Naccache, f. chen, m. palma, a. lemenze, w. Wu, p. mishra, h. eltzshig, s. c. robson, f. Di Virgilio, G. Hasko, w. gause
The paper shows that adenosine from extracellular ATP via A2BAR on intestinal epithelial cells promotes type 2 immunity against helminth infection.
bioRxiv · Jan 24, 2021Immunology