Author

F. Di Virgilio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2

Frequent Co-Authors

E. Adinolfi· 3 shared A. L. Giuliani· 2 shared E. De Marchi· 2 shared P. Boldrini· 2 shared S. Falzoni· 2 shared V. Vultaggio-Poma· 2 shared A. C. Sarti· 1 shared A. Gartland· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

E. Adinolfi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

P2X7-dependent exchange of extracellular microparticles and mitochondria by mouse microglia

S. Falzoni, P. Chiozzi, V. Vultaggio-Poma, M. Tarantini, E. Adinolfi, P. Boldrini, A. L. Giuliani, D. C. Gorecki, F. Di Virgilio

This study shows that P2X7R-dependent release of microparticles containing mitochondria and other molecules modulates energy metabolism and inflammation in mouse microglia.

bioRxiv · Apr 18, 2023 · PreprintCell Biology

A2A Receptor contributes to tumor progression in P2X7 null mice

E. De Marchi, A. Pegoraro, R. Turiello, F. Di Virgilio, S. Morello, E. Adinolfi

This study shows that A2A receptor contributes to tumor progression in P2X7 null mice by enhancing immunosuppression and vascularization.

bioRxiv · Feb 28, 2022 · PreprintCancer Biology

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

L. Tattersall, K. M. Shah, D. L. Lath, A. Singh, J. M. Down, E. De Marchi, A. Williamson, F. Di Virgilio, D. Heymann, E. Adinolfi, W. D. Fraser, D. Green, M. A. Lawson, A. Gartland

This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.

bioRxiv · May 7, 2021Cancer Biology

Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling on intestinal epithelial cells

d. w. El-Naccache, f. chen, m. palma, a. lemenze, w. Wu, p. mishra, h. eltzshig, s. c. robson, f. Di Virgilio, G. Hasko, w. gause

The paper shows that adenosine from extracellular ATP via A2BAR on intestinal epithelial cells promotes type 2 immunity against helminth infection.

bioRxiv · Jan 24, 2021Immunology

The P2X7 receptor localizes to the mitochondria, modulates mitochondrial energy metabolism and enhances physical performance

A. C. Sarti, V. Vultaggio-Poma, S. Falzoni, S. Missiroli, A. L. Giuliani, P. Boldrini, M. Bonora, F. Faita, N. Di Lascio, C. Kusmic, A. Solini, S. Novello, M. Morari, M. Rossato, M. R. Wieckowski, , F. Di Virgilio

bioRxiv · Sep 18, 2020 · PreprintCell Biology