YAP condensates are highly organized hubs for YAP/TEAD transcription
S. Hao, H. Fuehrer, E. Flores, J. Demmerle, J. Lippincott-Schwartz, Z. Liu, S. Sukenik, D. Cai
This study shows YAP forms organized condensates under Hippo pathway and actin tension, which stabilize YAP and recruit coactivators to enhance transcription.
bioRxiv · Oct 24, 2022Cell Biology