Desmosomal dualism: the core is stable while plakophilin is dynamic.
J. B. Fulle, H. Huppert, D. Liebl, J. Liu, R. Alves de Almeida, B. Yanes, G. D. Wright, E. B. Lane, D. R. Garrod, C. Ballestrem
The paper shows desmosomes have a stable core and a dynamic plakophilin module, with Pkp2a remaining mobile during desmosome maturation and down-regulation.
bioRxiv · Mar 2, 2021Cell Biology