Author

H. I. Needs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

I. Collinson· 3 shared J. Henley· 3 shared G. C. Pereira· 2 shared A. Witt· 1 shared E. Glover· 1 shared K. Wilkinson· 1 shared M. Dodding· 1 shared W. Hubner· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

I. Collinson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Intercellular Mitochondrial Transfer as a Rescue Mechanism in Response to Protein Import Failure

H. I. Needs, G. C. Pereira, E. Glover, A. Witt, W. Hubner, M. Dodding, J. Henley, I. Collinson

This study shows that mammalian cells can rescue mitochondrial protein import failure by transferring healthy mitochondria between cells via tunneling nanotubes.

bioRxiv · Nov 30, 2022 · PreprintCell Biology

Perturbation of the mitochondrial import machinery by aggregation prone Tau affects organelle morphology and reduces neuronal complexity

H. I. Needs, K. Wilkinson, J. Henley, I. Collinson

This study investigates how TauP301L affects mitochondrial import, morphology, and function in neurons, revealing a link between aggregation-prone proteins and neurodegeneration.

bioRxiv · Nov 30, 2022 · PreprintCell Biology

The NanoLuc Assay System for Accurate Real-Time Monitoring of Mitochondrial Protein Import within Intact Mammalian Cells

H. I. Needs, G. C. Pereira, J. Henley, I. Collinson

This paper develops a NanoLuc assay system to monitor mitochondrial protein import in live mammalian cells, enabling kinetic analysis and mechanistic insights into the process.

bioRxiv · Sep 23, 2022 · PreprintBiochemistry