ImmunologybioRxivPreprint
Classical macrophage polarisation is limited by human β-defensin 3 via an autocrine IL-4 dependent process.
M. E. Candela, D. J. P. Allsop, R. N. Carter…·J. R. Dorin
This paper shows HBD3 limits macrophage classical activation and promotes alternative activation via IL-4R, enabling a repair-conducive state.
DOI 10.1101/2021.05.06.442606