Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
17 papers
Recent·Most cited
P. C. Cook, S. L. Brown, E. L. Houlder, S. Baker, F. R. Svedberg, G. Howell, M. Bertuzzi, L. Boon, J. E. Konkel, J. E. Allen, A. S. MacDonald
The paper identifies Mgl2+ cDC2s as key drivers of type 2, but not type 17, fungal allergic airway inflammation in mice.
bioRxiv · Nov 24, 2023Immunology
J. E. Parkinson, A. D. Adamson, A. S. MacDonald, J. E. Allen, T. E. Sutherland
This study shows that targeting chitinase-like proteins can prevent or reverse allergen-induced airway matrix remodelling in mice, independent of ongoing inflammation.
bioRxiv · Aug 18, 2023 · PreprintImmunology
K. S. McLoughlin, D. Shi, J. E. Mast, J. Bucci, J. P. Williams, W. D. Jones, D. Miyao, L. Nam, H. L. Osswald, L. Zegelman, J. E. Allen, B. J. Bennion, A. K. Paulson, R. Abagyan, M. S. Head, J. M. Brase
The paper develops a generative molecular design platform, ATOM-GMD, to create selective histamine H1 inhibitors, which are validated experimentally with six compounds showing high potency and selectivity.
bioRxiv · Feb 14, 2023 · PreprintPharmacology & Toxicology
J. Ajendra, S. Pearson, J. Parkinson, B. H. K. Chan, H. J. McSorley, T. E. Sutherland, J. E. Allen
This study shows IL-17A promotes IL-33 production in lung epithelial cells during nematode infection, independent of IFN-gamma suppression.
bioRxiv · Nov 3, 2022 · PreprintImmunology
R. Sahputra, K. Dejyong, A. Woolf, M. Mack, J. E. Allen, D. Ruckerl, S. Herrick
This study shows that monocyte-derived peritoneal macrophages reduce surgery-induced adhesions in C57BL/6 mice, while BALB/c mice show increased adhesions with reduced monocyte influx.
bioRxiv · Jul 12, 2022 · PreprintImmunology
C. M. Finlay, J. Parkinson, B. H. Chan, J. Ajendra, A. Chenery, A. Morrison, E. L. Houlder, S. M. Baker, B. Dickie, L. Boon, A. S. MacDonald, J. E. Konkel, D. Rückerl, J. E. Allen
This study shows that host genetics and Th2 cells influence monocyte-to-tissue-resident-macrophage differentiation during nematode infection in mice.
bioRxiv · Dec 17, 2021 · PreprintImmunology
P. H. Papotto, B. Yilmaz, G. Pimenta, S. Mensurado, C. Cunha, G. J. Fiala, D. Gomes da Costa, N. Goncalves-Sousa, B. H. K. Chan, B. Blankenhaus, T. Carvalho, A. J. Macpherson, J. E. Allen, B. Silva-Santos
This study shows maternal γδ T cells influence offspring pulmonary type-2 immunity through microbiota-dependent mechanisms, affecting gut-lung axis development and inflammation.
bioRxiv · Aug 13, 2021Immunology
A. N. Donlan, J. L. Leslie, M. E. Simpson, W. A. Petri, J. E. Allen, W. A. Petri
This study shows IL-13 protects against C. difficile infection by promoting recovery and regulating macrophage polarization and monocyte dynamics.
bioRxiv · Aug 3, 2021 · PreprintImmunology
M. E. Candela, D. J. P. Allsop, R. N. Carter, F. Semple, F. Kilanowski, S. Webb, D. Taggart, H. J. W. Mullan, B. J. McHugh, D. H. Dockrell, D. J. Davidson, J. E. Allen, S. J. Jenkins, N. M. Morton, J. R. Dorin
This paper shows HBD3 limits macrophage classical activation and promotes alternative activation via IL-4R, enabling a repair-conducive state.
bioRxiv · May 6, 2021 · PreprintImmunology
R. Forman, L. B. Logunova, H. Smith, K. Wenyss, I. Mair, L. Boon, J. E. Allen, W. Müller, J. L. Pennock, K. J. Else
This study shows that RELMα+ Ym1+ macrophages in the large intestine can upregulate these markers without IL4R signaling, challenging the idea that IL4/IL13 is required for their activation.
bioRxiv · Dec 17, 2020Immunology
A. L. Chenery, S. Rosini, J. Parkinson, J. A. Herrera, C. Lawless, B. H. Chan, P. A. Loke, A. S. MacDonald, K. Kadler, T. E. Sutherland, J. E. Allen
This study shows that IL-13 reduces lung damage and supports epithelial type 2 molecule production during nematode infection in mice.
bioRxiv · Oct 14, 2020Immunology
J. Ajendra, A. L. Chenery, J. E. Parkinson, B. H. Chan, S. Pearson, S. A. Colombo, L. Boon, R. K. Grencis, T. E. Sutherland, J. E. Allen
This study shows IL-17A suppresses IFNγ to initiate and later limits type-2 immune responses in the lung during nematode infection.
bioRxiv · Apr 18, 2020Immunology
A. F. Hurlstone, F. Bottiglione, C. T. Dee, R. Lea, L. Zeef, A. P. Badrock, M. Wane, L. Bugeon, M. J. Dallman, J. E. Allen
The paper investigates the roles of IL-4-like and IL-10 cytokines in zebrafish gill homeostasis and inflammation, finding that IL-10 is essential while IL-4-like cytokines are not.
bioRxiv · Apr 9, 2020Immunology
K. J. Mylonas, L. H. Jackson-Jones, J. P. M. Andrews, M. S. Magalhaes, M. Meloni, N. V. Joshi, J. E. Allen, D. E. Newby, M. R. Dweck, G. A. Gray, C. A. Benezech
This study shows that the pericardium promotes cardiac repair and reduces mortality after myocardial infarction by regulating inflammation and macrophage polarization.
bioRxiv · Sep 18, 2019 · PreprintPhysiology
I. S. Toor, D. Ruckerl, I. Mair, R. Ainsworth, M. Meloni, A.-M. Spiroski, J. M. Felton, A. Thomson, A. Caporali, T. Keeble, K. Tang, A. G. Rossi, D. E. Newby, J. E. Allen, G. A. Gray
This study shows that eosinophil deficiency after myocardial infarction leads to adverse cardiac remodeling, which can be mitigated by IL-4 therapy.
bioRxiv · Sep 9, 2019Immunology
A. Chenery, R. Alhallaf, Z. Agha, J. Ajendra, J. Parkinson, M. M. Cooper, B. H. Chan, R. M. Eichenberger, L. A. Dent, A. A. Robertson, A. Kupz, D. Brough, A. Loukas, T. E. Sutherland, J. E. Allen, P. Giacomin
This study shows NLRP3 limits lung neutrophilia and helminth killing in an inflammasome-independent way, while promoting tissue repair.
bioRxiv · Jun 7, 2019Immunology