DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation
Z. Hou, P. M. Wydorski, V. A. Perez, A. Mendoza-Oliva, B. D. Ryder, H. Mirbaha, O. Kashmer, L. A. Joachimiak
This study identifies DnaJC7's interaction with tau's beta-turn element to inhibit amyloid formation, suggesting a mechanism for tau aggregation regulation.
bioRxiv · Dec 15, 2020Biophysics