BiophysicsbioRxiv
The allosteric activation of α7 nAChR by α-conotoxin MrIC is modified by mutations at the vestibular site
A. Gulsevin, R. L. Papke, C. Stokes…·J. Meiler
This paper shows that α-conotoxin MrIC activates α7 nAChR allosterically through a vestibular site, confirmed by electrophysiology and computational docking.
DOI 10.3390/toxins13080555