Saturation of influenza virus neutralization and antibody consumption can both lead to bistable growth kinetics
S. Xu, A. W. C. Yan, H. Peck, L. Gillespie, I. G. Barr, X. Yang, S. J. Turner, C. M. Donato, T. Zhang, M. Olshansky, V. Dhanasekaran
The paper uses mathematical models and focus reduction assays to show that influenza virus neutralization and antibody consumption can lead to bistable growth kinetics, explaining reinfection and vaccine efficacy.
bioRxiv · Mar 2, 2020 · PreprintMicrobiology