Author

H. R. Schoeler

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Biophysics· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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C. M. MacCarthy· 1 shared J. Huertas· 1 shared V. Cojocaru· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiophysics

C. M. MacCarthy

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1 paper

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BiophysicsbioRxivMay 10, 2019

Nucleosomal DNA dynamics mediate Oct4 pioneer factor binding

J. Huertas, C. M. MacCarthy, H. R. Schoeler, V. Cojocaru

This study shows that nucleosome dynamics enable Oct4 binding by correlating mobility with binding site availability and stable protein-DNA interactions.

DOI 10.1016/j.bpj.2019.12.038

ChIP-seqstructural biology

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