Engineering of extracellular vesicles for display of protein biotherapeutics
D. Gupta, O. P. B. Wiklander, A. Gorgens, M. Conceicao, G. Corso, X. Liang, Y. Seow, S. Balsu, U. Felldin, B. Bostancioglu, Y. X. F. Lee, J. Hean, I. Mager, T. C. Roberts, M. Gustafsson, , S. E. Andaloussi
This paper develops a platform to display multiple protein therapeutics on extracellular vesicles, showing improved efficacy in inflammatory disease models compared to existing biologics.
bioRxiv · Jun 14, 2020Bioengineering