Substrate-binding Glycine Residues are Major Determinants for Hydrolase and Ligase Activity of Plant Legumains
X. Hemu, N.-Y. Chan, H. T. Liew, S. Hu, X. Zhang, A. Serra, J. Lescar, C.-F. Liu, J. P. Tam
The paper identifies conserved glycine residues as key determinants distinguishing peptide asparaginyl ligases (PALs) from asparaginyl endopeptidases (AEPs) in plant legumains.
bioRxiv · Sep 26, 2022Plant Biology